Myxobacteria: natural pharmaceutical factories

نویسندگان

  • Juana Diez
  • Javier P Martinez
  • Jordi Mestres
  • Florenz Sasse
  • Ronald Frank
  • Andreas Meyerhans
چکیده

Myxobacteria are amongst the top producers of natural products. The diversity and unique structural properties of their secondary metabolites is what make these social microbes highly attractive for drug discovery. Screening of products derived from these bacteria has revealed a puzzling amount of hits against infectious and non-infectious human diseases. Preying mainly on other bacteria and fungi, why would these ancient hunters manufacture compounds beneficial for us? The answer may be the targeting of shared processes and structural features conserved throughout evolution.

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عنوان ژورنال:

دوره 11  شماره 

صفحات  -

تاریخ انتشار 2012